Please consult the latest official manual style if you have any questions regarding the format accuracy. Figure 8-1 shows the general xanthine structure and the structures of theophylline (1,3-dimethylxanthine) and caffeine (1,3,7-trimethylxanthine). Specific xanthine agents. Liver disease. Monitor BP if patient is also on antihypertensive treatment. Contrast the therapeutic effects of leukotriene antagonists, glucocorticoids, cromolyn, antihistamines, and mucolytics for COPD and asthma. Disclaimer: These citations have been automatically generated based on the information we have and it may not be 100% accurate. Find patient medical information for Duoneb Inhalation on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Caffeine: (Major) Methylxanthines, through antagonism of adenosine and thus pharmacologic-induced coronary vasodilation, have been associated with false-negative results during dipyridamole-thallium 201 stress testing. METHYLXANTHINES EXPECTED OUTCOMES? METHYLXANTHINES PATIENT TEACHING? Although nursing considerations and implications are slightly different, most nursing resources and textbooks use them interchangeably. Therefore, a calm approach is an important aspect of care. Describe the therapeutic serum or plasma theophylline level and the toxic level. Methylxanthines; Nursing Management. • Phenobarbital and phenytoin decrease theophylline levels. Start studying MCC nursing 1355. Theophylline is related chemically to the natural metabolite xanthine, which is a precursor of uric acid. Nursing Implications. cAMP so bronchodilation -decr. Assessment & Drug Effects. Citation. Methylxanthines -inhibits phosphodiesterase leads to incr. Narrow margin of safety & high risk of toxicity - SX: anorexia, N/V, restlessness, insomnia, seizures, dysrhythmias. IV Therapeutic Level: 10 - 20. Methylxanthines (nursing considerations: • Advise clients to avoid consuming caffeinated beverages (coffee, caffeinated colas). The patient and family are often frightened and anxious because of the patient’s dyspnea. Reginald P. Sequeira, in Side Effects of Drugs Annual, 2009. Learn vocabulary, terms, and more with flashcards, games, and other study tools. METHYLXANTHINES NURSING IMPLICATIONS? Monitor therapeutic effectiveness which is indicated by relief from pain and cramping in calf muscles, buttocks, thighs, and feet during exercise and improves walking performance (time and duration). Methylxanthines are bronchodilators used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). histamine release -stimulates ciliary transport of ... Drug Mechanism Use Side/Adverse Effects Nursing Implications Cromolyn Sodium (non-steroidal) INTAL -prevents influx of Ca into mast cells, therefore inhibiting degranulation and release of The immediate nursing care of patients with asthma depends on the severity of symptoms. Less frequent nocturnal asthma. It is recommended that caffeine be discontinued for at least 24 hours prior to stress testing. Because of their methyl attachments, these agents are often referred to as methylxanthines. Describe the side effects of beta 2-adrenergic agonists and methylxanthines.